
Los Santos Holidays from AU$1,307
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Your Los Santos Holiday
Embark on a journey full of discovery and excitement with a holiday package to Los Santos. Known for its festivals and so much more, this destination will surprise and delight at every step. A trip to Los Santos wouldn't be complete without spending some time in its best cities, starting with Pedasi. Some of the top attractions here include Iguana Island National Park and Playa El Arenal. Las Tablas is another favourite with Los Santos travellers. Visitors to this exciting city enjoy El Uverito Beach and Playa Las Comadres. Expedia has everything you need for organising your Los Santos holiday. From flights and accommodation, to rental cars and activities, we're here to help you curate a travel experience like no other.
The Latest Los Santos Holiday Deals

Megapolis Hotel Panamá
Reviewed on 26 Nov 2025

Central Hotel Panama Casco Viejo
Reviewed on 23 Nov 2025

Amarla Boutique Hotel Casco Viejo
Reviewed on 18 Nov 2025

Casa Lefevre By Wynwood House
Reviewed on 8 Sept 2025

Yoo by Wynwood House
Reviewed on 26 July 2025
Los Santos Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Tocumen Intl. Airport (PTY) |
Top Sights | Venao Beach, El Uverito Beach and Los Destiladeros Beach |
Our pick of the best Los Santos Hotel Deals

Villa Marina Lodge & Condos
Great news place, 2 min from all the loud places but it has charm and very nice. Great family room for people traveling with teens
Reviewed on 25 Nov 2025

Hotel Posada Destiladeros
The sea view was amazing and it had easy access to the beach. The breakfast was lovely. The hosts are very helpful. The restaurant evening meal was wonderful, we had fresh fish and shrimp. A good selection of drinks was also available. A short drive from Pedasi. We also saw a yellow caracara at breakfast ...
Reviewed on 18 Sept 2025

Hotel Presidente
Yes
Reviewed on 26 Nov 2025













